Home – Institute for Personalized and Translational Medicine

At the forefront of biomedical research, personalized medicine integrates genetic, molecular, and clinical data to deliver more targeted and effective healthcare solutions

OUR STORY

Despite unprecedented scientific breakthroughs made in recent years, a dramatically wide gap remains between understanding biological processes in the human body and practical tools used in conventional medicine. Translational medicine may be compared to “Esperanto”, as it is accepted by both medical and research communities for combining efforts and facilitating advanced scientific, sophisticated and productive solutions for real life applications.

IPTM, established in 2014 by Dr. Igor Koman at Ariel University, aims to enrich translational technologies by evoking the philosophy of personalization to find exclusive solutions for individual patients’ unmet clinical needs. Our team, which includes experts in biological sciences and medicine, views the patient as a complete holistic system, in which all individual parameters are linked to one another, each having equal value and the potential to influence the final outcome. By adhering to a patient-centered approach, we develop two parallel, but tightly interrelated arms of our research activities: identification of unique individual therapeutic targets and an intensive search for safe and highly effective agents acting towards these targets.

RESEARCH DIRECTIONS

Gut–Brain Axis

Personalized Psychiatry

Translational and personalized oncology

OUR ARTICLES

How cannabis during pregnancy affects offspring differently

This study found that prenatal cannabis exposure affects offspring differently based on their temperament. “Resilient” mice became more anxious, while “sensitive” mice became more social and less anxious. The findings highlight that the effects of cannabis during pregnancy are complex and depend on individual personality traits.

A simple gut supplement in mothers may improve their babies’ health and behavior

Our study found that improving a mother’s gut health after birth—using a simple supplement—can lead to calmer, more social, and metabolically healthier offspring. The effect was especially strong in males, showing how a mother’s gut can shape her babies’ development in surprising ways.

A new 3D model (Assembloids) that recreates a patient’s gastric cancer more realistically

Our researchers developed a new lab model that mimics a patient’s stomach cancer more accurately by combining tumor cells with surrounding support cells. This approach better reflects how tumors behave in the body and may help predict which treatments will work for each individual patient.