Breast cancer is the leading cause of cancer-related deaths among women, and current treatments don’t always work the same for everyone. One big challenge is that doctors often don’t know in advance which chemotherapy will be most effective for each patient.

In this study, our researchers developed a new way to grow 3D “mini-tumors” in the lab using breast cancer tissue taken directly from patients. These lab-grown tumor spheroids closely resemble the original tumor in the patient’s body. Scientists tested different chemotherapy drugs on the mini-tumors to see how each one responded.

They found that responses to treatment varied between patients – some mini-tumors were sensitive to certain drugs, while others were not. This method could help dectors predict which traetments are most likely to work for each individual, allowing for more personilized and effective care.

This approach shows great promise for improving outcomes in breast cancer by helping match the right treatment to the right patient.